Slow, tight-binding inhibition of PDF by actinonin induces

Frédéric Dardel's research works Paris Descartes University, Paris and other places

Peptide Deformylase Inhibitors as Antibacterial Agents: Identification of VRC3375, a Proline-3-Alkylsuccinyl Hydroxamate Derivative, by Using an Integrated Combinatorial and Medicinal Chemistry Approach

Accurate quantitative determination of affinity and binding kinetics for tight binding inhibition of xanthine oxidase - ScienceDirect

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

Total synthesis of (±)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors - ScienceDirect

Full article: Atomic level and structural understanding of natural ligands inhibiting Helicobacter pylori peptide deformylase through ligand and receptor based screening, SIFT, molecular dynamics and DFT – a structural computational approach

Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development

Carmela GIGLIONE, Laboratory Head, PhD, Université Paris-Saclay, Paris

A [(32)P]NAD(+)-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors. - Abstract - Europe PMC

Closed and half-open states of LiPDF. A, the closed state within the