Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach

Jon WINTER-HOLT, Senior medicinal chemist, AstraZeneca, London, AZ, Oncology iMED

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

Synthetic Approaches to New Drugs Approved during 2018

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

The chemistry and applications of hafnium and cerium( iv ) metal–organic frameworks - Chemical Society Reviews (RSC Publishing) DOI:10.1039/D0CS00920B

Chemical modulation of Kv7 potassium channels - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00328J

VX-745 - an overview ScienceDirect Topics

Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa)

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

Christina CHAN, Researcher, PhD, AstraZeneca, London, AZ, Drug Metabolism & Pharmacokinetics (DMPK)

Molecules, Free Full-Text

Design of Hedgehog pathway inhibitors for cancer treatment. - Abstract - Europe PMC