tVNS in POTS

Postural orthostatic tachycardia syndrome (POTS) is a chronic debilitating condition of orthostatic intolerance, predominantly affecting young
Postural orthostatic tachycardia syndrome (POTS) is a chronic debilitating condition of orthostatic intolerance, predominantly affecting young females. Other than postural tachycardia, symptoms of POTS include a spectrum of non-cardiac, systemic and neuropsychiatric features. Despite the availability of widespread pharmacological and non-pharmacological therapeutic options, the management of POTS remains challenging. Exaggerated parasympathetic withdrawal and sympathetic overdrive during postural stress are principal mechanisms of postural tachycardia in POTS. Non-invasive, transcutaneous, vagus nerve stimulation (tVNS) is known to restore sympathovagal balance and is emerging as a novel therapeutic strategy in cardiovascular conditions including arrhythmias and heart failure. Furthermore, tVNS also exerts immunomodulatory and anti-inflammatory effects. This review explores the effects of tVNS on the pathophysiology of POTS and its potential as an alternative nonpharmacological option in this condition.

Atrial Arrhythmias

Transcutaneous Vagus Nerve Stimulation (tVNS)

tVNS in POTS

Vagus Nerve Stimulation for POTS - Johns Hopkins Medicine

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Vagus Nerve Stimulation in POTS - Andre Diedrich, MD, PhD

TENS Ear Clips for Vagus Nerve Stimulation, Dual

Transcutaneous Vagus Nerve Stimulation - Drop It Like It's POTS

Transdermal auricular vagus stimulation for the treatment of